Haraldson – tuber fleeceflower. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Most species are considered weedy, especially in moist soils in the USA. [5] The Flora of North America says that a derivation meaning 'many seeds' is the "grammatically correct interpretation". Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. The genus name is usually said to be from the Greek πολυ- (poly-, 'many') and γόνυ (gonu, 'knee' or 'joint'), in reference to the swollen jointed stem. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Fo-Ti is believed to als… Evidence of hepatic injury in humans exists; consider P. multiflorum and its extracts hepatotoxic. Raw, wine- or steam-processed, or cured fo-ti is available in the United States.1, 2, 3, 4, Radix Polygoni multiflori or he shou wu is a popular Chinese tonic herb, whose usage dates back to 713 AD.2 Fo-ti appears to be a name given to the preparation for use in areas where Chinese is not the primary language.4 It is considered one of the country's great 4 herbal tonics, along with angelica, lycium, and panax, and is used to increase liver and kidney function and to cleanse the blood.3 The plant is also prescribed for symptoms of premature aging, such as gray hair, and is commonly found in hair care products in China.2, 4 It is also used to treat insomnia, weak bones, constipation, and atherosclerosis.2 Regarded as a rejuvenating plant, fo-ti has been thought to prevent aging and promote longevity. (He Shou Wu in Chinese pinyin, hereinafter referred to as HSW) is the root ofPolygonum multiflorum, a member of Polygonaceae. Embryonic toxicity has been reported. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This product may be unsafe when used before surgery or other medical procedures. Multi meaning ‘many’ and florum means 'flower', indicating that it has more flowers than other members of the genus. MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE. The flowers are usually bisexual, rarely unisexual, and have five (occasionally four) tepals, the outer being slightly different from the inner ones. Prepare as a tea or tonic, or as directed by a physician. 1,2,3 18, … A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. Common names include knotweed and knotgrass (though the common names may refer more broadly to plants from Polygonaceae). Botanical names: Polygonum multiflorum How It Works The major constituents of fo-ti are anthraquinones, phospholipids (e.g., lecithin), tannins, and tetrahydroxystilbene glucoside. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. As a Chinese herb, it was recorded most early in “Kaibao Bencao” published by the imperial court of the Song Dynasty (973-974 A.D.) [1 1. 5 Historical Use of Polygonum multiflorum. Directions: To use as a tea, pour 1 cup boiling water over 1 tsp. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. [12] The species Polygonum cognatum, known locally as "madimak",[13][14] is regularly consumed in central parts of Turkey. The plant may also be nephro-, neuro-, and embryotoxic. It is known as tuber fleeceflower and Chinese knotweed. The species name multiflorum refers to the flowers. Fo-Ti or He Shou Wu is considered a powerful longevity herb in the system of Chinese Medicine. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Clinical trials are lacking to support claims for therapeutic purposes, but topical applications for the treatment of alopecia and a role in neurodegenerative diseases are being investigated. We comply with the HONcode standard for trustworthy health information -. Reynoutria multiflora ( synonyms Fallopia multiflora and Polygonum multiflorum) is a species of flowering plant in the buckwheat family Polygonaceae. Sorting Polygonum names. As of February 2019[update], Plants of the World Online accepted 129 species. Common Name: He Shou Wu. Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum multiflorus Common Names Chinese Knotweed, Climbing Knotweed, Fo ti, Flowery Knotweed, He-Shou-Wu, Kashuu Last updated on Dec 12, 2019. Hepatotoxicity has been documented.50, 51, 52 GI symptoms, including diarrhea, may be due to consuming raw or improperly processed fo-ti.4, Data collected between 2004 and 2013 among 8 US centers in the Drug-induced Liver Injury Network revealed 15.5% (130) of hepatotoxicity cases was caused by herbals and dietary supplements whereas 85% (709) were related to medications. Botanical Name: Polygonum multiflorum. 10.1 Other Names: 11 Historical Use of Polygonum multiflorum. When the genus is defined narrowly, Polygonum species are annual or perennial herbaceous plants, rarely shrubby, with much branched stems. Net Weight :250g. Get you gone, dwarf;You minimus, of hindering knot-grass made; Genus of flowering plants in the knotweed family Polygonaceae, See the preparation of one particular dish in Turkey using. Within the tribe, it is most closely related to the genera Duma and Atraphaxis, forming the so-called "DAP clade". Haraldson. The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. Fallopia multiflora (Thunb.) Liver transplant was also more frequent with toxicity from non-bodybuilding supplements (13%) than with conventional medications (3%) (P<0.001). Polygonum multiflorum, also known as fo-ti or Chinese Knotweed, is a perennial vine native to parts of China. Polygonum multiflorum Thunb. The roots are the main plant part of interest and are harvested and dried in autumn when they are 3 to 4 years of age, but the stems and leaves are also used. It is probably best known for it’s ability to turn grey hair dark again. The leaves are arranged alternately, usually less than 2 cm (0.8 in) long, with a length greater than the width. Ho-shou-wu (pinyin: heshouwu) is derived from the roots of Polygonum multiflorum.The herb was first recorded (1,2,16) in the Ri Huazi Bencao (Tang Dynasty, 713 A.D.) and then incorporated into the well-known Kaibao Bencao (Song Dynasty; 973 A.D.). Other reviews suggest an idiopathic nature to the toxicity, with more than 400 cases reported. P. multiflorum is widely used in Chinese medicine; however, adverse event reporting under clinical trial conditions is lacking. Discussing the plant he knew as polygonum in 1655, Matthias Martinius referred to Scribonius Largus (who wrote a list of prescriptions around 47 AD) and gave an alternative etymology, based on γόνος (gonos, 'offspring', 'seed'), the meaning of the name then being the Latin foecundus, i.e. Embryonic toxicity has been reported.53, Case reports are lacking. Clinical trials reporting on efficacy are limited.4, A mixture including he shou wu has been studied for its effects on the glucocorticoid receptor in senile rat thymocytes.15 An effect of emoghrelin, derived from P. multiflorum, stimulated growth hormone in vitro,16 and tetrahydroxystilbene glucoside protected against the thinning of mice derma associated with aging.17 Lifespan and lipid studies of he shou wu in quails have been performed.18, There are no clinical data regarding the use of P. multiflorum for antiaging effects. Directions. General Information Polygonum multiflorum is a Perennial Climber up to 4.50 metres tall. Planta Med 2010;76(9):889-92. Plant Description: Chinese knotweed is a herbaceous vine, which quickly spreads and covers any available surfaces. : 823837 (Download Help) Polygonum multiflorum TSN 823837 Taxonomy and Nomenclature Kingdom: Plantae : Taxonomic Rank: Species : Common Name(s): tuber fleeceflower [English] Accepted Name(s): Fallopia multiflora (Thunb.) A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day. Polygonatum multiflorum. Polygonum is a genus in the Polygonaceae family. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. They are longish-elliptical with short stalks and rounded bases ; … P. multiflorum is native to central and southern China and is also distributed in Japan and Taiwan. Other Common Names: Climbing knotweed, flowery knotweed, fo-ti, fo-ti-teng, he shou wu, or ho shou wu. Common name(s): Solomon’s Seal, David’s Harp, Ladder-to-Heaven Synonyme(s): N/A Family: Asparagaceae, Nolinoideae subfamily Origin: Asia (Caucasus, Nepal, Turkey), Europe More infos: A variegated cultivar is available. [6], Many members of the family Polygonaceae that are now placed in separate genera were at one time or other placed in Polygonum, including species of Fagopyrum, Fallopia, Persicaria and Reynoutria,[7] and older sources frequently use much wider definitions of the genus. The plant is self-fertile. Evidence exists of hepatic injury in humans. P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. Of the 217 supplement products implicated in liver injury, fo-ti was among the 22% (116) of the single-ingredient products.55, Reviews of the toxic effects, possibly dose- and duration-related, of P. multiflorum on the liver have been published. hypoleucum It is native to Central and southern China. Of page the name Polygonum aviculare knotgrass herb tea is pleasant for centuries, Polygonum multiflorum has used! Other genera, such as Polygonella, have been subsumed into Polygonum. The genus primarily grows in northern temperate regions. Fo-Ti is widely used to strengthen the lower back and knees. Polygonum multiflorum var. In the Middle English glossary of herbs Alphita (c. 1400-1425), it was known as ars-smerte. 5.1 Polygonum multiflorum in Traditional Chinese Medicine; 6 Background; 7 Nomenclature. According to folklore, the older and larger roots have the most power, potentially offering immortality.2, 3, 4, Major chemical constituents include stilbenes, quinones, flavonoids phospholipids, and others. Other genera, such as Polygonella, have been subsumed into Polygonum. View abstract. Hepatotoxicity has been documented. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Some synonyms are listed below.[10]. This root has been cured in a soy bean solution during processing. Global Biodiversity Information Facility. You should talk with your health care provider for complete information about the risks and benefits of using this product. 'fecund', 'with many offspring'. Former genera such as Polygonella have been subsumed into Polygonum; other genera have been split off. Polygonum multiflorum Thunb. This information is not specific medical advice and does not replace information you receive from your health care provider. Species on this page ( A = names approved by most authorities, s = approved as synonyms) : Polygonum affine D. Don s -> Fallopia aubertii (L. Henry) Holub A; Polygonum amphibium L. -> Persicaria amphibia (L.) Gray; Polygonum amplexicaule D. Don; Polygonum aubertii L. Henry s-> Fallopia aubertii (L. Henry) Holub A It has been used for thousands of years to promote long life, nourish blood, strengthen bones, tendons and muscles as well as many other purposes. In The Man Who Laughs Victor Hugo wrote of the Comprachicos (child-buyers) who created artificial dwarfs, formed "by anointing babies' spines with the grease of bats, moles and dormice" and using drugs such as "dwarf elder, knotgrass, and daisy juice". Medically reviewed by Drugs.com. Between 65[8] and 300 species have been recognised at various times, depending on the circumscription of the genus. An in vitro study suggests tetrahydroxystilbene glucoside exerts an inhibitory effect on platelet aggregation.29, P. multiflorum is widely used in Chinese medicine; however, adverse event reporting under clinical trial conditions is lacking. Available for Android and iOS devices. Powders are great for encapsulating. Emodin has demonstrated inhibitory effects on vasodilation in isolated rat aortas.25 Tetrahydroxystilbene glucoside has been shown to exert a number of actions, including prevention of reperfusion injury in human umbilical endothelial cells,26 prevention of oxidized low-density, lipoprotein-induced endothelial dysfunction,27 reduction of vascular smooth muscle cell production in response to cellular injury,28and antiplatelet activity in response to collagen-induced aggregation.29. Purported antiaging effects mostly rely on in vitro studies of antioxidant and neuroprotective effects.5, Topical application of P. multiflorum has to induced follicular keratinocyte proliferation in mice.19, 20 The inhibition of tyrosinase activity in mice melanocytes has also been demonstrated,21 and compounds isolated from P. multiflorum roots induced a greater proliferation of dermal papilla cells than minoxidil in an in vitro study.22. The Plants Database includes the following 83 species of Polygonum . Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Taxonomic Serial No. The idea of such use was also known to Shakespeare, as Beatrice K. Otto pointed out, quoting A Midsummer Night's Dream:[15]. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. There are usually four to six stamens and three (rarely two) styles. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Common names include knotweed, knotgrass, bistort, tearthumb, mile-a-minute, smartweed and several others. [7] In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. hypoleucum, syn. Suitable pH: acid, neutral and basic (alkaline) soils. Polygonum L. – knotweed Species: Polygonum multiflorum Thunb. There are no clinical data regarding the use of P. multiflorum in cardiovascular-related disorders. The processed (cured) root of the plant is used to make medicine. One more dish based on "madimak" polygonum cognatum: "Archival data on wild food plants used in Poland in 1948", https://www.youtube.com/watch?v=DzNCO94rWXE, https://www.youtube.com/watch?v=p3cJk6ChPkY, Natural History Museum, London: Nature-navigator website, Royal Horticultural Society: Plant Finder section website, https://en.wikipedia.org/w/index.php?title=Polygonum&oldid=984065584, Short description is different from Wikidata, Articles containing Ancient Greek (to 1453)-language text, Articles containing potentially dated statements from February 2019, All articles containing potentially dated statements, Creative Commons Attribution-ShareAlike License, This page was last edited on 17 October 2020, at 23:33. There are no clinical data regarding the use of P. multiflorum in cancer. Polygonum species are occasionally eaten by humans, and are used as food plants by the larvae of some Lepidoptera species – see list. Molecular phylogenetic studies, particularly in the 21st century, have led to major changes. The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. Latin Name Common Name Habit Height Hardiness Growth Soil Shade Moisture Edible Medicinal Other; Polygonum alaskanum: Alaska Wild Rhubarb: Perennial: 1.8 - LMH: SN: M: 2: 1 : Polygonum alpinum: Alpine Knotweed, Alaska wild rhubarb: Perennial: 1.0: 4-8 LMH: SN: M: 2: 1 [3][4] However, long before Linnaeus, the name was used in Greek and Latin for a plant used medically. Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice. Polygonum multiflorum Thunb. Polygonum hydropiper is a ANNUAL growing to 0.8 m (2ft 7in). The fruit is three-sided. Fallopia ciliinodis). Lin HW, Sun MX, Wang YH, et al. No Image. There are no clinical data regarding the use of P. multiflorum in alopecia or hair coloring despite widespread traditional use in China for this purpose. This is especially helpful to older people. .mw-parser-output table.clade{border-spacing:0;margin:0;font-size:100%;line-height:100%;border-collapse:separate;width:auto}.mw-parser-output table.clade table.clade{width:100%;line-height:inherit}.mw-parser-output table.clade td.clade-label{width:0.7em;padding:0 0.15em;vertical-align:bottom;text-align:center;border-left:1px solid;border-bottom:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-fixed-width{overflow:hidden;text-overflow:ellipsis}.mw-parser-output table.clade td.clade-fixed-width:hover{overflow:visible}.mw-parser-output table.clade td.clade-label.first{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-label.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-slabel{padding:0 0.15em;vertical-align:top;text-align:center;border-left:1px solid;white-space:nowrap}.mw-parser-output table.clade td.clade-slabel:hover{overflow:visible}.mw-parser-output table.clade td.clade-slabel.last{border-left:none;border-right:none}.mw-parser-output table.clade td.clade-slabel.reverse{border-left:none;border-right:1px solid}.mw-parser-output table.clade td.clade-bar{vertical-align:middle;text-align:left;padding:0 0.5em;position:relative}.mw-parser-output table.clade td.clade-bar.reverse{text-align:right;position:relative}.mw-parser-output table.clade td.clade-leaf{border:0;padding:0;text-align:left}.mw-parser-output table.clade td.clade-leafR{border:0;padding:0;text-align:right}.mw-parser-output table.clade td.clade-leaf.reverse{text-align:right}.mw-parser-output table.clade:hover span.linkA{background-color:yellow}.mw-parser-output table.clade:hover span.linkB{background-color:green}, Polygonum ciliinode (syn. Um MY, Choi WH, Aan JY, Kim SR, Ha TY. Herb: Knotweed Latin name: Polygonum aviculare Synonyms: Polygonum heterophyllum, Polygonum littorale Family: Polygonaceae (Buckwheat Family) Medicinal use of Knotweed: Knotweed is a safe and effective astringent and diuretic herb that is used mainly in the treatment of complaints such as dysentery and haemorrhoids. Fo Ti or Fleeceflower Root Powder (common name)/ He Shou Wu (Pin Yin name) / Polygonum Multiflorum Root (botanical name). It is in flower from July to September. WHAT'S IN AN HERB NAME? For example, buckwheat (Fagopyrum esculentum) has sometimes been included in the genus as Polygonum fagopyrum. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Contains some soy. They have a membranous ochrea (a sheath around the stem nodes). In vitro studies and limited animal data suggest P. multiflorum extracts, tetrahydroxystilbene glucoside and emodin, possess anticancer properties.5, 12, 23, 24 The focus of research into antiapoptotic activity centers on neuroprotection against degenerative disease (see CNS). This information relates to an herbal, vitamin, mineral or other dietary supplement. Of the 130 related cases of liver injury related to supplements, 65% were from non-bodybuilding supplements and occurred most often in Hispanic/Latinos compared to non-Hispanic whites and non-Hispanic blacks. This information should not be used to decide whether or not to take this product. Hepatotoxicity is largely reversible; however, deaths have been reported.50, 51, 52 Nephrotoxicity and embryonic toxicity53 have also been reported and attributed to the quinone constituents emodin and rhein.5, 37, Tetrahydroxystilbene glucoside and emodin appear to have neuro-, nephro-, and hepatoprotective effects.30, 32, 43, 48, 54 In mice, processing the raw roots increased emodin and decreased tetrahydroxystilbene glucoside content and diminished observed toxicity.13, In rats, tetrahydroxystilbene glucoside was detected in the liver and lungs in the highest concentrations, but not in brain and testes tissues.6 Mutagenicity and toxicity to lung tissue have also been described.5. Free and Open Access to Biodiversity Data. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. It is a perennial climbing herb that can grow to 9 m in height. Radix Polygoni multiflori or he shou wu is a popular Chinese tonic herb, whose usage dates back to 713 AD.2 Fo-ti appears to be a name given to the preparation for use in areas where Chinese is not the primary language.4 It is considered one of the country's great 4 herbal tonics, along with angelica, lycium, and panax, and is used to increase liver and kidney function and to cleanse the blood.3 The plant is also prescribed for symptoms of premature aging, such as gray hair, and is commonly found in hair care pro… Q. T. Chen, L. H. Zhuo, W. Xu, Z. H. Huang, and X. H. Qiu, “Content changes of 5 components in Polygohum muhiflorum during processing,” Chinese Journal of Experimental Traditional Medical Formulae, vol. The species is hermaphrodite (has both male and female organs). 1 Fleeceflower root is widely produced across China, including in the Henan, Hubei, Guizhou, provinces.